Exscientia vs Smartly vs Open Paper: Which Exploit Development tool is Best in 2025?

All these tools Exscientia , Smartly , Open Paper offer flexible pricing models suitable for Penetration Testers, Ethical Hackers, Cybersecurity Students, and Security Analysts seeking AI-powered solutions to enhance their Exploit Development efforts.

Exscientia

Starting from
custom

Smartly

Starting from
custom

Open Paper

Starting from
$12/month

These AI tools are among the best Exploit Development tools available in 2025. For Penetration Testers, Ethical Hackers, Cybersecurity Students, and Security Analysts, tools like Exscientia , Smartly , Open Paper help streamline the Exploit Development process by offering AI-powered features.

What is Exscientia?

Exscientia, founded in 2012 in Oxford, UK, is a trailblazing AI-driven drug discovery platform for precision medicine that leverages artificial intelligence to revolutionize pharmaceutical development. Acquired by Recursion Pharmaceuticals in November 2024, Exscientia combines AI, automation, and patient-centric data to design safer, more effective drugs faster. With over $450 million in milestone payments and a pipeline of more than 10 clinical and preclinical programs, patient-first AI for drug development has delivered the first three AI-designed drugs to clinical trials, achieving 10 times productivity gains. Trusted by partners like Sanofi and Bristol Myers Squibb, Exscientia operates globally, focusing on oncology and beyond.

What is Smartly?

Smartly, founded in 2013 by Kristo Ovaska and Tuomo Riekko in Helsinki, Finland, is a cutting-edge AI-powered advertising platform for performance that unifies creative, media, and analytics to streamline digital advertising. Managing over $5 billion in ad spend for 700+ brands like Nike and Uber, Smartly leverages generative AI to produce 1 billion creative variants daily, enhancing campaigns across Meta, TikTok, Google, and more. Its cross-channel ad automation for brands delivers 3.3x faster campaign setup and up to 5.5x return on ad spend, making it a top choice for enterprise-level marketing.

What is Open Paper?

Open Paper is an AI-powered platform that helps users read, annotate, and understand research papers more effectively. It offers features like an AI assistant with contextual citations, allowing users to ask questions and get trusted responses linked to the paper. You can also annotate papers, listen to audio summaries, find related research, and share insights with others.

Exscientia
(4.5/5)
  • Accuracy and Reliability:
    4.7
  • Cost-Efficiency:
    4.5
  • Customization and Flexibility:
    4.8
  • Data Privacy and Security:
    4.6
  • Ease of Use:
    4.5
  • Functionality and Features:
    4.4
  • Integration Capabilities:
    4.3
  • Performance and Speed:
    4.2
  • Support and Resources:
    4.7
Smartly
(4.5/5)
  • Accuracy and Reliability:
    4.6
  • Cost-Efficiency:
    4.5
  • Customization and Flexibility:
    4.8
  • Data Privacy and Security:
    4.7
  • Ease of Use:
    4.6
  • Functionality and Features:
    4.4
  • Integration Capabilities:
    4.2
  • Performance and Speed:
    4.3
  • Support and Resources:
    4.8
Open Paper
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Exscientia
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Smartly
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Open Paper
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Exscientia

Pros

10x faster drug discovery.

95% accurate drug response predictions.

30% cost reduction in R&D.

Scalable AWS-powered platform.

Strong partnerships with Sanofi and Merck.

Cons

Requires technical expertise.

Minor third-party data privacy risks.

High initial costs for small firms.

Occasional support delays.

Smartly

Pros

3.3x faster campaign setup.

5.5x ROAS with predictive AI.

Seamless Meta and TikTok integrations.

1 billion daily creative variants.

28% lower CPA with analytics.

Cons

Steep learning curve for beginners.

Slow chat support response.

1 billion daily creative variants.

28% lower CPA with analytics.

Not Enough Data!

If you're looking for other Exploit Development tools for Penetration Testers, Ethical Hackers, Cybersecurity Students, and Security Analysts, you can also explore Ghidra, Radare2, which are highly rated in 2025.

Exscientia
  • Exscientia
  • Oxford, UK
Smartly
  • Smartly
  • Helsinki, Finland
Open Paper
  • Open Paper
  • San Francisco